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产品属性：
产品名称 | 1-Stearoyl-2-Arachidonoyl-d8-sn-glycero-3-PC |
规格 | 50 μg、100 μg、500 μg、1 mg |
货号 | EY-01Y9586 |
Cas No.: 161922-50-5
别名: N/A
化学名: N/A
分子式: C46H76D8NO8P
分子量: 818.2
溶解度: Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
1-Stearoyl-2-arachidonoyl-d8-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC by GC- or LC-MS. 1-Stearoyl-2-arachidonoyl-sn-glycero-3-PC (SAPC) is a phospholipid containing stearic acid and arachidonic acid at the sn-1 and sn-2 positions, respectively. It is a component of LDL and has been found in human stenotic aortic valves and atherosclerotic plaques.1,2 Levels of SAPC are increased in the subepithelial invasive region compared to the superficial region of tumor tissue samples from patients with superficial-type pharyngeal squamous cell carcinoma.3 SAPC unilamellar vesicles have been used as substrates to quantify the activity of secretory phospholipase A2 (sPLA2) in the presence or absence of inhibitors.4 SAPC has also been used in the formation of lipid bilayers to study the effects of lipid composition on bilayer phase transitions.5 1.Milne, G.L., Seal, J.R., Havrilla, C.M., et al.Identification and analysis of products formed from phospholipids in the free radical oxidation of human low density lipoproteinsJ. Lipid Res.46(2)307-319(2005)
2.Lehti, S., KÄkelÄ, R., HÖrkkÖ, S., et al.Modified lipoprotein-derived lipid particles accumulate in human stenotic aortic valvesPLoS One8(6)e65810(2013)
3.Ishikawa, S., Tateya, I., Hayasaka, T., et al.The distribution of phosphatidylcholine species in superficial-type pharyngeal carcinomaBiomed. Res. Int.5387913(2017)
4.Schebb, N.H., Falck, D., Faber, H., et al.Fast method for monitoring phospholipase A2 activity by liquid chromatography-electrospray ionization mass spectrometryJ. Chromatogr. A1216(27)5249-5255(2009)
5.Tada, K., Goto, M., Tamai, N., et al.Pressure effect on the bilayer phase transition of asymmetric lipids with an unsaturated acyl chainAnn. N.Y. Acad. Sci.1189(1)77-85(2010)
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