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产品属性：
产品名称 | 7-Chloro-4-(piperazin-1-yl)quinoline |
规格 | 100 mg、250 mg |
货号 | EY-01Y9878 |
Cas No.: 837-52-5
别名: N/A
化学名: N/A
分子式: C13H14ClN3
分子量: 247.72
溶解度: DMSO : 16.67 mg/mL (67.29 mM; ultrasonic and warming and heat to 60°C)
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
7-Chloro-4-(piperazin-1-yl)quinolone is an important scaffold in medicinal chemistry. 7-Chloro-4-(piperazin-1-yl)quinolone is a potent sirtuin inhibitor and also inhibits the serotonin uptake (IC50 of 50 μM). 7-Chloro-4-(piperazin-1-yl)quinolone exhibits antimalarial activity on D10 and K1 strains of P. falciparum with IC50s of 1.18 μM and 0.97 μM, respectively[1].[1]. Aida M Abd El-Sattar El-Azzouny, et al. Structural and biological survey of 7-chloro-4-(piperazin-1-yl)quinoline and its derivatives. Drug Dev Res. 2020 Nov;81(7):786-802.
特别提醒公司产品仅供科研使用
