上海一研生物科技有限公司

产品属性：

Cas No.: 7020-34-0

别名: N/A

化学名: N/A

分子式: C30H48O2

分子量: 440.7

溶解度: DMF: 30 mg/ml,DMSO: 10 mg/ml,Ethanol: 10 mg/ml

储存条件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.

Shipping ConditionEvaluation sample solution : ship with blue ice

All other available size: ship with RT , or blue ice upon request

产品描述：

3-Oxobetulin is a pentacyclic triterpenoid and derivative of betulinic acid that has been found in I. macropoda and has diverse biological activities.1,2,3 It is active against the plant pathogenic fungi L. betulina and L. sulphureus when used at a concentration of 30 µg/ml.2 3-Oxobetulin reduces HIV-1 replication in MT-2 cells (IC50 = 4.1 µM) with a 50% cytotoxic concentration (CC50) value of greater than 100 µM.4 It inhibits cadmium-induced cytotoxicity in HepG2 cells in a concentration-dependent manner.31.Kim, D.K., Nam, I.Y., Kim, J.W., et al.Pentacyclic triterpenoids from Ilex macropodaArch. Pharm. Res.25(5)617-620(2002)2.Chien, S.-C., Xiao, J.-H., Tseng, Y.-H., et al.Composition and antifungal activity of balsam from Liquidambar formosana HanceHolzforschung67(3)345-351(2013)3.Hiroya, K., Takahashi, T., Miura, N., et al.Synthesis of betulin derivatives and their protective effects against the cytotoxicity of cadmiumBioorg. Med. Chem.10(10)3229-3236(2002)4.Callies, O., Bedoya, L.M., BeltrÁn, M., et al.Isolation, structural modification, and HIV inhibition of pentacyclic lupane-type triterpenoids from Cassine xylocarpa and Maytenus cuzcoinaJ. Nat. Prod.78(5)1045-1055(2015)
特别提醒公司产品仅供科研使用