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产品属性：
产品名称 | (E/Z)-IT-603 |
规格 | 5 mg、10 mg、25 mg、50 mg、100 mg |
货号 | EY-01Y10367 |
Cas No.: 292168-90-2
别名: N/A
化学名: N/A
分子式: C11H9BrN2O3S
分子量: 329.17
溶解度: DMSO: 125 mg/mL (379.74 mM)
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
(E/Z)-IT-603 is a mixture of E-IT-603 and Z-IT-603 (IT-603). IT-603 is a c-Rel inhibitor with an IC50 of 3 μM. IT-603 has anti-tumor activity. (E/Z)-IT-603 is a promising modulator of T-cell responses in the context of graft-versus-host disease (GVHD) and malignant diseases[1].[1]. Yusuke Shono, et al. A small molecule c-Rel inhibitor reduces alloactivation of T-cells without compromising anti-tumor activity. Cancer Discov. 2014 May; 4(5): 578-591.
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