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产品属性：
产品名称 | 4-hydroperoxy Cyclophosphamide |
规格 | 5mg、10mg |
货号 | EY-01Y10417 |
Cas No.: 39800-16-3
别名: 4-OOH-CY
化学名: 2-[bis(2-chloroethyl)amino]tetrahydro-2-oxido-2H-1,3,2-oxazaphosphorin-4-yl, hydroperoxide
分子式: C7H15Cl2N2O4P
分子量: 293.1
溶解度: 30mg/mL in DMSO,Souble in chloroform and dichloromethane. Prepare for immediate use. Do not store after dissloved
储存条件: Store at -80°C, protect from light, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
4-hydroperoxy Cyclophosphamide (4-OOH-CY) is the active metabolite form of the prodrug Cyclophosphamide. 4-OOH-CY crosslinks DNA and induces T cell apoptosis independent of death receptor activation, but activates mitochondrial death pathways through production of reactive oxygen species (ROS).[1] Formulations containing the prodrug Cyclophosphamide are used to treat lymphomas and autoimmune disorders.[2],[3]
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