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产品属性：
产品名称 | 9(E),11(E)-12-nitro Conjugated Linoleic Acid |
规格 | 50 μg、100 μg、250 μg、500 μg |
货号 | EY-01Y10535 |
Cas No.: 1515620-30-0
别名: N/A
化学名: N/A
分子式: C18H31NO4
分子量: 325.4
溶解度: 0.1 M Na2CO3: 1mg/mL,DMF: 50mg/mL,DMSO: 50mg/mL,Ethanol: 50mg/mL
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
9(E),11(E)-12-nitro Conjugated linoleic acid (9(E),11(E)-12-nitro CLA) is a nitrated fatty acid. It is formed from 9(Z),11(E)-CLA upon exposure to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or a combination of myeloperoxidase, hydrogen peroxide, and nitrite.1 It is also formed in LPS-stimulated RAW 264.7 macrophages, an effect that can be reduced by the nitric oxide synthase (NOS) inhibitor L-NAME .2 9(E),11(E)-12-nitro CLA has been found in human plasma.1.Woodcock, S.R., Salvatore, S.R., Bonacci, G., et al.Biomimetic nitration of conjugated linoleic acid: Formation and characterization of naturally occurring conjugated nitrodienesJ. Org. Chem.79(1)25-33(2014)
2.Bonacci, G., Baker, P.R.S., Salvatore, S.R., et al.Conjugated linoleic acid is a preferential substrate for fatty acid nitrationJ. Biol. Chem.287(53)44071-44082(2012)
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