产品属性:
产品名称 | 7,8-Dihydroneopterin |
规格 | 5mg、10mg、25mg |
货号 | EY-01Y10691 |
Cas No.: 1218-98-0
别名: D-erythro-7,8-Dihydroneopterin
化学名: 2-amino-7,8-dihydro-6-[(1S,2R)-1,2,3-trihydroxypropyl]-4(3H)-pteridinone
分子式: C9H13N5O4
分子量: 255.2
溶解度: 0.3 mg/ml in DMF, 1 mg/ml in DMSO
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
7,8-Dihydroneopterin is a pteridine with antioxidant activities.[1] It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay when used at concentrations ranging from 20 to 100 μM. 7,8-Dihydroneopterin (2-10 μM) inhibits copper ion-induced oxidation of LDL in a cell-free assay and decreases thiobarbituric acid reactive substances (TBARS) produced by THP-1 cells cultured with LDL.[2],[3] It inhibits necrosis induced by oxidized LDL (oxLDL) in U937, but not THP-1, cells when used at a concentration of 200 μM.[4]
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