5-ALA benzyl ester hydrochloride
5-ALA benzyl ester hydrochloride
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产品属性:


产品名称

5-ALA benzyl ester hydrochloride

规格

10mg、25mg、50mg、100mg、200mg、500mg

货号

EY-01Y10920

Cas No.: 163271-32-7

别名: N/A

化学名: N/A

分子式: C12H16ClNO3
GC38882.png
分子量: 257.71

溶解度: DMSO: 250 mg/mL (970.08 mM)

储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.

Shipping ConditionEvaluation sample solution : ship with blue ice

All other available size: ship with RT , or blue ice upon request

产品描述:


5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) is a protoporphyrin precursor used as a photodetection agent. 5-ALA benzyl ester hydrochloride induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines[1][2].5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) (0.6-0.12 mM; 3 h) induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines SW480[2].Reducing the dose of 5-ALA benzyl ester hydrochloride (31 mg/kg; i.v. ; 1 hours) results in a dose-dependent reduction in tumour porphyrin levels[3].Animal Model:Female CBA/Gy mouse (CaNT tumour model)[3][1]. Hirschberg H, et al. ALA- and ALA-ester-mediated photodynamic therapy of human glioma spheroids. J Neurooncol. 2002 Mar;57(1):1-7.[2]. Brunner H, et al. The effects of 5-aminolevulinic acid esters on protoporphyrin IX production in human adenocarcinoma cell lines. Photochem Photobiol. 2001 Nov;74(5):721-5.[3]. Tunstall RG, et al. Porphyrin accumulation induced by 5-aminolaevulinic acid esters in tumour cells growing in vitro and in vivo. Br J Cancer. 2002 Jul 15;87(2):246-50.
特别提醒公司产品仅供科研使用


英文名称
5-ALA benzyl ester hydrochloride
货号
EY-01Y10920
CAS
163271-32-7
含量
>98.00%
规格
10mg、25mg、50mg、100mg、200mg、500mg
品牌
上海一研
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