上海一研生物科技有限公司

产品属性：

Cas No.: 2304-89-4

别名: 3-Dehydrocholic Acid

化学名: (5β,7α,12α)-7,12-dihydroxy-3-oxo-cholan-24-oic acid

分子式: C24H38O5

分子量: 406.6

溶解度: 30mg/mL in DMSO, 30mg/mL in DMF, 30mg/mL in Ethanol

储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.

Shipping ConditionEvaluation sample solution : ship with blue ice

All other available size: ship with RT , or blue ice upon request

产品描述：

3-Oxocholic acid is a secondary bile acid and a metabolite of cholic acid in C. perfringens, a bacteria found in the intestines of mammals and in the environment.[1],[2] 3-Oxocholic acid serum levels increase following ileal transposition surgery in rats.[3]

References[1]. Wahlstr•m, A., Sayin, S.I., Marschall, H.-I., et al. Intestinal crosstalk between bile acids and microbiota and its impact on host metabolism. Cell Metab. 24(1), 41-50 (2016).[2]. Macdonald, I.A., Forrest, T.P., Costain, G.A., et al. Identification of 7α-, 12α-dihydroxy-3-oxo cholanoic acid as the major degradation product from cholic by C. perfringens. J. Steroid Biochem. 9(4), 353-358 (1978).[3]. Yan, K., Chen, W., Zhu, H., et al. The changes of serum metabolites in diabetic GK rats after ileal transposition surgery. Obes. Surg. 29(3), 882-890 (2019).
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