产品属性:
产品名称 | 6-O-desmethyl Donepezil |
规格 | 500μg、1mg、5mg |
货号 | EY-01Y11142 |
Cas No.: 120013-56-1
别名: N/A
化学名: N/A
分子式: C23H27NO3
分子量: 365.5
溶解度: Chloroform: soluble,Methanol: soluble
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
6-O-desmethyl Donepezil is an active metabolite of the acetylcholinesterase inhibitor donepezil . It is formed through dealkylation by the cytochrome P450 (CYP) isoform CYP2D6. It inhibits human ether a go-go (hERG) channels (IC50 = 1.5 µM in HEK293 cells expressing hERG).
特别提醒公司产品仅供科研使用