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产品属性：
产品名称 | 4-Bromo-3-hydroxybenzoic acid |
规格 | 100mg |
货号 | EY-01Y11177 |
Cas No.: 14348-38-0
别名: N/A
化学名: N/A
分子式: C7H5BrO3
分子量: 217.02
溶解度: Soluble in DMSO
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
4-Bromo-3-hydroxybenzoic acid is a metabolite of Brocresine and a histidine decarboxylase (HDC) inhibitor with IC50s of 1 mM for both rat fetal and rat gastric HDC. 4-Bromo-3-hydroxybenzoic acid also inhibits aromatic-L-amino acid decarboxylase from hog kidney and rat gastric mucosa in vitro with IC50s of 1 mM for both enzymes[1][2].[1]. Ellenbogen L, et al. Studies on the inhibition of histidine decarboxylase, aromatic-L-amino acid decarboxylase and acid secretion by brocresine and its metabolites. Biochem Pharmacol. 1973 Apr 15;22(8):939-47.
[2]. Qian S, et al. Inhibiting Histamine Signaling Ameliorates Vertigo Induced by Sleep Deprivation. J Mol Neurosci. 2019 Mar;67(3):411-417.
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