- 产品详情
- 产品参数
- 产品评论
产品属性：
产品名称 | (3S)-hydroxy Quinidine |
规格 | 500μg、1mg |
货号 | EY-01Y11507 |
Cas No.: 53467-23-5
别名: N/A
化学名: N/A
分子式: C20H24N2O3
分子量: 340.4
溶解度: Methanol: Soluble
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
(3S)-hydroxy Quinidine is an active quinidine metabolite. Quinidine, an antiarrhythmic agent, undergoes rapid first-pass metabolism by the cytochrome P450 (CYP) isoforms CYP3A4, CYP2C9, CYP2E1, and CYP3A5, with CYP3A4 being the most active enzyme in the (3S)-hydroxy quinidine formation. (3S)-hydroxy Quinidine prolongs repolarization of canine Purkinje fibers in vitro and prevents ventricular fibrillation and ventricular tachycardia after coronary reperfusion in isolated rat hearts in a dose-dependent manner.
特别提醒公司产品仅供科研使用
