产品属性:
产品名称 | 17α-hydroxy Pregnenolone |
规格 | 100mg、250mg、500mg、1g |
货号 | EY-01Y11578 |
Cas No.: 387-79-1
别名: NSC 63853
化学名: 3β,17-dihydroxy-pregn-5-en-20-one
分子式: C21H32O3
分子量: 332.5
溶解度: 0.5mg/mL in DMSO
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
17α-hydroxy Pregnenolone is a metabolite of pregnenolone and a precursor in the biosynthesis of dehydroepiandrosterone .[1] It is formed from pregnenolone by cytochrome P450 (CYP) isoform CYP17A1 hydroxylase activity and then converted to dehydroepiandrosterone by CYP17A1-mediated 17,20-lyase activity. Plasma levels of 17α-hydroxy pregnenolone are elevated in patients with type II 3β-hydroxysteroid dehydrogenase deficiency, a form of congenital adrenal hyperplasia.[2]
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