上海一研生物科技有限公司

产品属性：

Cas No.: 59403-54-2

别名: N/A

化学名: N/A

分子式: C46H80NO8P

分子量: 806.1

溶解度: Chloroform: Slightly soluble

储存条件: Store at -80°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.

Shipping ConditionEvaluation sample solution : ship with blue ice

All other available size: ship with RT , or blue ice upon request

产品描述：

1-Palmitoyl-2-docosahexaenoyl-sn-glycero-3-PC (PDPC) is a phospholipid that contains palmitic acid and docosahexaenoic acid at the sn-1 and sn-2 positions, respectively. It is a component of LDL and HDL and has been found in atherosclerotic plaques.1,2 Enrichment of PDPC in recombinant HDLs decreases cholesterol ester formation by lecithin:cholesterol acyltransferase (LCAT) in vitro.3,41.Davis, B., Koster, G., Douet, L.J., et al.Electrospray ionization mass spectrometry identifies substrates and products of lipoprotein-associated phospholipase A2 in oxidized human low density lipoproteinJ. Biol. Chem.283(10)6428-6437(2008)

2.MÉnÉgaut, L., Masson, D., Abello, N., et al.Specific enrichment of 2-arachidonoyl-lysophosphatidylcholine in carotid atheroma plaque from type 2 diabetic patientsAtherosclerosis251339-347(2016)

3.Parks, J.S., Thuren, T.Y., and Schmitt, J.D.Inhibition of lecithin:cholesterol acyltransferase activity by synthetic phosphatidylcholine species containing eicosapentaenoic acid or docosahexaenoic acid in the sn-2 positionJ. Lipid Res.33(6)879-887(1992)

4.Parks, J.S., and Gebre, A.K.Long-chain polyunsaturated fatty acids in the sn-2 position of phosphatidylcholine decrease the stability of recombinant high density lipoprotein apolipoprotein A-I and the activation energy of the lecithin:cholesterol acyltransferase reactionJ. Lipid Res.38(2)266-275(1997)
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