上海一研生物科技有限公司

产品属性：

Cas No.: 2628-17-3

别名: N/A

化学名: N/A

分子式: C8H8O

分子量: 120.15

溶解度: N/A

储存条件: -20°C, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.

Shipping ConditionEvaluation sample solution : ship with blue ice

All other available size: ship with RT , or blue ice upon request

产品描述：

4-Vinylphenol is found in the medicinal herb Hedyotis diffusa Willd, wild rice and is also the metabolite of p-coumaric and ferulic acid by lactic acid bacteria in wine. 4-Vinylphenol induces apoptosis and inhibits blood vessels formation and suppresses invasive breast tumor growth in vivo[1].4-Vinylphenol (12.5-200 µg/mL) significantly reduces cell viability in parental MDA-MB-231 cells, and the IC50 value is 109 µg/mL[1]. 4-Vinylphenol (0.15 or 0.3 µg/mL; 3 days) reduces sphere?formation and vimentin expression on CSCs in breast cancer[1]. 4-Vinylphenol (50, 100 µg/mL; 72 hours) significantly suppresses cell proliferation in CSC-enriched MDA-MB-231 cells. 4-Vinylphenol significantly reduces ALDH1A1 expression by 50% in CSC-enriched MDA-MB-231 cells[1]. 4-Vinylphenol (100 µg/mL) significantly increases the expressions of caspase 3, likely sensitizing CSC-enriched MDAMB-231 cells to apoptosis[1]. [1]. Leung HW, et al. The natural agent 4-vinylphenol targets metastasis and stemness features in breast cancer stem-like cells. Cancer Chemother Pharmacol. 2018 Aug;82(2):185-197.
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