- 产品详情
- 产品参数
- 产品评论
产品属性：
产品名称 | 5-hydroxymethyl Tolterodine (formate) |
规格 | 1mg |
货号 | EY-01Y11827 |
Cas No.: 380636-49-7
别名: N/A
化学名: N/A
分子式: C22H31NO2•CH2O2
分子量: 387.5
溶解度: DMSO: soluble,Methanol: soluble
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
5-hydroxymethyl Tolterodine is an active metabolite of the muscarinic acetylcholine receptor antagonists tolterodine and fesoterodine . It is formed from tolterodine by the cytochrome P450 (CYP) isoform CYP2D6 and from fesoterodine by plasma esterases. 5-hydroxymethyl Tolterodine inhibits M1-5 muscarinic receptors with Ki values of 2.3, 2, 2.5, 2.8, and 2.9 nM, respectively, for the human receptors expressed in CHO cells. It selectively inhibits acetylcholine-induced bladder contraction over electrically induced salivation in anesthetized cats (ID50s = 15 and 40 nmol/kg, respectively).
特别提醒公司产品仅供科研使用
