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产品属性：
产品名称 | Amyloid-β (17-40) Peptide (human) (trifluoroacetate salt) |
规格 | 500μg、1mg |
货号 | EY-01Y11899 |
Cas No.: N/A
别名: N/A
化学名: N/A
分子式: C110H178N26O31S•XCF3COOH
分子量: 2392.8
溶解度: Formic Acid: 1 mg/ml
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
Amyloid-β (Aβ) (17-40) is a 24-residue fragment of the Aβ protein that is formed via post-translational processing of amyloid precursor protein (APP) by α- and γ-secretases. In vitro, Aβ (17-40) polymerizes into lattice-like structures that do not bind thioflavin T. It inhibits interactions between fibrinogen and biotinylated Aβ (1-42) as well as between cholesterol and apolipoprotein E (ApoE) with IC50 values of 13.4 and 25 μM, respectively. Aβ (17-40) increases the rate of Aβ (1-40) aggregation in vitro when used at an equimolar concentration. Aβ (17-40) (25 μM) induces cell death in cultured rat hippocampal neurons.
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