产品属性:
产品名称 | Amyloid-β Precursor Protein (96-110) Peptide (cyclized) (human) (trifluoroacetate salt) |
规格 | 1mg |
货号 | EY-01Y11927 |
Cas No.: N/A
别名: N/A
化学名: N/A
分子式: C81H128N32O19S2 ? XCF3COOH
分子量: 1918.2
溶解度: Water: 1 mg/ml
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
Amyloid-β precursor protein (96-110) peptide (cyclized) is a synthetic peptide consisting of amino acids 96-110 of amyloid precursor peptide (APP) that is cyclized via a bridge between the cysteine residues at positions 3 and 10. It is homologous to the heparin-binding domain of human APP and inhibits binding of [125I]APP to heparin in vitro with an IC50 value of approximately 100 nM. Amyloid-β precursor protein (96-110) peptide (cyclized) inhibits neurite outgrowth induced by APP and mouse postnatal heparan sulfate proteoglycans (HSPG) in primary mouse hippocampal neurons when used at a concentration of 10 μg/ml.
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