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产品属性：
产品名称 | Amyloid β-Peptide (10-20) (human) |
规格 | 1mg、5mg、10mg、25mg |
货号 | EY-01Y11957 |
Cas No.: 152286-31-2
别名: Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe
化学名: Amyloid β-Peptide (10-20) (human)
分子式: C71H99N17O16
分子量: 1446.67
溶解度: ≥ 144.7mg/mL in DMSO
储存条件: Desiccate at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
The amyloid β-peptide (Aβ) has a central role in initiating neurodegeneration in Alzheimer disease (AD) 1. It is widely believed to be an incidental catabolic byproduct of the amyloid β protein precursor (APP) with no normal physiological function.2
Aβ has been shown to be a ligand for a number of different receptors and other molecules3-5. It is transported between tissues and across the blood brain barrierby complex trafficking pathways6. Aβ is modulated in response to a variety of environmental stressors and is able to induce pro-inflammatory activities7.
Soluble amyloid β-peptide fragment that is a substrate for gelatinase A/type IV collagenase/MMP-2 and APP secretase; cleaved between Lys16 and Leu17.
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