产品属性:
产品名称 | Dynamin inhibitory peptide, myristoylated |
规格 | 1 mg |
货号 | EY-01Y11956 |
Cas No.: 251634-22-7
别名: N/A
化学名: N/A
分子式: C61H107N19O14
分子量: 1330.64
溶解度: Soluble in DMSO
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
Cell-permeable version of dynamin inhibitory peptide, an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. Reduces NMDA receptor internalization. Control Peptide also available.Grabs et al (1997) The SH3 domain of amphiphysin binds the proline-rich domain of dynamin at a single site that defines a new SH3 binding consensus sequence. J.Biol.Chem. 272 13419 PMID:9148966 |Kittler et al (2000) Constitutive endocytosis of GABAA receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons. J.Neurosci. 20 7972 PMID:11050117 |Nong et al (2003) Glycine binding primes NMDA receptor internalization. Nature 422 302 PMID:12646920
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