产品属性:
产品名称 | Amyloid-β (1-38) Peptide (trifluoroacetate salt) |
规格 | 500μg、1mg |
货号 | EY-01Y12036 |
Cas No.: N/A
别名: N/A
化学名: N/A
分子式: C184H277N51O56S•XCF3COOH
分子量: 4131.6
溶解度: Formic Acid: 1 mg/ml
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
Amyloid-β (1-38) (Aβ38) peptide is a fragment of the Aβ42 peptide . It has been found in isolated human cerebrospinal fluid from a patient with Alzheimer's disease. Aβ38 (20-80 µM) enhances glutamate-induced neurotoxicity in cultured fetal human cerebral cortical neurons but does not affect neuronal survival when used alone or astrocyte survival when used alone or in combination with glutamate. It increases intracellular calcium levels in cultured fetal human cerebral cortical neurons when used in combination with glutamate. Aβ38 also enhances neurotoxicity of neurons cultured in calcium-containing medium but not calcium-deficient medium.
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