产品属性:
产品名称 | Gramicidin A |
规格 | 1mg、5mg |
货号 | EY-01Y12037 |
Cas No.: 11029-61-1
别名: N/A
化学名: N/A
分子式: C99H140N20O17
分子量: 1882.3
溶解度: DMSO: soluble,Ethanol: soluble,Water: slightly soluble
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
Gramicidin A is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis. Gramicidin A is a highly hydrophobic channel-forming ionophore that forms channels in model membranes that are permeable to monovalent cations. It induces degradation of hypoxia inducible factor 1 α (HIF-1α) in HEK293 cells and reduces growth in a human renal cell carcinoma mouse xenograft model when administered at a dose of 0.22 mg/kg three times per week. Gramicidin A has commonly been used to study channel structure and function.
特别提醒公司产品仅供科研使用