产品属性:
产品名称 | (Gln²²,Asn²³)-Amyloid β-Protein (1-40) |
规格 | 0.5mg、1mg |
货号 | EY-01Y11993 |
Cas No.: 374796-75-5
别名: N/A
化学名: N/A
分子式: C194H297N55O56S
分子量: 4327.9
溶解度: Soluble in DMSO
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
Transgenic mice expressing the vasculotropic Dutch/Iowa (E693Q/D694N) mutant human Aβ precursor protein in brain (Tg-SwDI) accumulate abundant cerebral microvascular fibrillar amyloid deposits and exhibit robust neuroinflammation. In vitro, the doubly mutated Aβ peptides showed an increased propensity to fibrillation and pathogenicity compared to the Dutch and Iowa single mutants.
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