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产品属性：
产品名称 | (Arg⁶)-Amyloid β-Protein (1-40) |
规格 | 0.5mg、1mg |
货号 | EY-01Y12009 |
Cas No.: 1802084-26-9
别名: N/A
化学名: N/A
分子式: C194H300N54O58S
分子量: 4348.91
溶解度: Soluble in DMSO
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
The English (H6R) mutation of β-amyloid peptides accelerates fibrillation without increasing protofibril formation. Ono et al. showed that the English and Tottori mutations alter Abeta assembly at its earliest stages, monomer folding and oligomerization, and produce oligomers that are more toxic to cultured neuronal cells than are wild type oligomers.
The exchange of His? by Arg influences the structure of the Cu(II) complex formed by Aβ peptides.
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