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产品属性：
产品名称 | FC131 TFA |
规格 | 1mg、5mg |
货号 | EY-01Y12146 |
Cas No.: N/A
别名: N/A
化学名: N/A
分子式: C38H48F3N11O8
分子量: 843.85
溶解度: DMSO: 250 mg/mL (296.26 mM)
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
FC131 TFA is a CXCR4 antagonist, inhibits [125I]-SDF-1 binding to CXCR4, with an IC50 of 4.5 nM. Anti-HIV activity[1].IC50: 4.5 nM ([125I]-SDF-1-CXCR4)[1]HIV-1[1][1]. Tamamura H, et al. Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131. J Med Chem. 2005 Jan 27;48(2):380-91.
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