产品属性:
产品名称 | [Sar9,Met(O2)11]-Substance P TFA |
规格 | 1mg、5mg、10mg、25mg、50mg、100mg |
货号 | EY-01Y12191 |
Cas No.: N/A
别名: N/A
化学名: N/A
分子式: C66H101N18F3O17S
分子量: 1507.68
溶解度: H2O: 100 mg/mL (66.33 mM)
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
[Sar9,Met(O2)11]-Substance P TFA is a tachykinin NK1 receptor selective agonist.[Sar9,Met(O2)11]-Substance P and septide (10-100 pmol per rat, i.c.v.) are equipotent in increasing mean arterial blood pressure (MAP) and heart rate (HR), yet they have dissimilar time-course. Both agonists increase dose-dependently face washing and sniffing while [Sar9,Met(O2)11]-Substance P is the sole to produce grooming[1].[1]. Cellier E, et al. Characterization of central and peripheral effects of septide with the use of five tachykinin NK1 receptor antagonists in the rat. Br J Pharmacol. 1999 Jun;127(3):717-28.
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