产品属性:
产品名称 | 9-ING-41 |
规格 | 10mM (in 1mL DMSO、)5mg、10mg、25mg、50mg、100mg |
货号 | EY-01Y12403 |
Cas No.: 1034895-42-5
别名: N/A
化学名: N/A
分子式: C22H13FN2O5
分子量: 404.35
溶解度: DMSO: 250 mg/mL (618.28 mM)
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
9-ING-41 is a potent glycogen synthase kinase-3 (GSK-3) inhibitor[1]. 9-ING-41 induces apoptosis and cell cycle arrest at prophase by targeting centrosomes and microtubule-bound GSK-3β. 9-ING-41 has anticancer activity[2].[1]. Ugolkov AV, et al. 9-ING-41, a small-molecule glycogen synthase kinase-3 inhibitor, is active in neuroblastoma. Anticancer Drugs. 2018 Sep;29(8):717-724.
[2]. Wu X, et al. Targeting glycogen synthase kinase 3 for therapeutic benefit in lymphoma. Blood. 2019 Jul 25;134(4):363-373.
特别提醒公司产品仅供科研使用