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产品属性：
产品名称 | (+)-JQ1 PA |
规格 | Free Sample (0.1-0.5 mg)、10mM*1mL in DMSO、5mg、10mg、25mg、50mg、100mg、200mg、500mg |
货号 | EY-01Y12562 |
Cas No.: 2115701-93-2
别名: N/A
化学名: N/A
分子式: C22H20ClN5OS
分子量: 437.95
溶解度: Ethanol: 50 mg/mL (114.17 mM)
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
(+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1, with an IC50 of 10.4 nM.10.4 nM (BET)[1].(+)-JQ1 PA is a derivative of JQ1, which is the inhibitor of BET. The IC50 of (+)-JQ1 PA for BET is 10.4 nM, and the IC50 of JQ1 is 14.3 nM in MV4;11 cells[1].[1]. Tyler DS, et al. Click chemistry enables preclinical evaluation of targeted epigenetic therapies. Science. 2017 Jun 30;356(6345):1397-1401.
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