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产品属性：
产品名称 | ALK-IN-5 |
规格 | 100mg、250mg、500mg |
货号 | EY-01Y12781 |
Cas No.: N/A
别名: N/A
化学名: N/A
分子式: C24H25FN6O3
分子量: 464.49
溶解度: Soluble in DMSO
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
ALK-IN-5 is a potent, selective, and brain-penetrant inhibitor of anaplastic lymphoma kinase (ALK), with an IC50 of 2.9 nM[1].IC50: 2.9 nM (ALK)[1]ALK-IN-5 potently inhibits ALK with cellular IC50 of 27 nM[1].[1]. Fushimi M, et al. Discovery of Potent, Selective, and Brain-Penetrant 1 H-Pyrazol-5-yl-1 H-pyrrolo[2,3- b]pyridines as Anaplastic Lymphoma Kinase (ALK) Inhibitors. J Med Chem. 2019 May 23;62(10):4915-4935.
特别提醒公司产品仅供科研使用
