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产品属性：
产品名称 | Abemaciclib Metabolites M2 |
规格 | 1mg、5mg |
货号 | EY-01Y13033 |
Cas No.: 1231930-57-6
别名: N/A
化学名: N/A
分子式: C25H28F2N8
分子量: 478.54
溶解度: Soluble in DMSO
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
Abemaciclib Metabolites M2 is a metabolite of abemaciclib, acts as a potent CDK4 and CDK6 inhibitor, with IC50s in the range of 1-3 nM. Anti-cancer activity[1].
CDK4|1-3 nM (IC50)|CDK6|1-3 nM (IC50)
[1]. Teresa Burke, et al. Abstract 2830: The major human metabolites of abemaciclib are inhibitors of CDK4 and CDK6. Cancer Research. July 2016, 76 (14).
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