5'-Thymidylic Acid (sodium salt)
5'-Thymidylic Acid (sodium salt)
收藏
¥0.00
收藏
正品保证
快速发货
  • 产品详情
  • 产品参数
  • 产品评论

产品属性:


产品名称

5'-Thymidylic Acid (sodium salt)

规格

100mg、250mg、1g

货号

EY-01Y13089

Cas No.: 33430-62-5

别名: N/A

化学名: N/A

分子式: C10H13N2O8P•2Na
GC48662.png
分子量: 366.2

溶解度: PBS (pH 7.2): slightly soluble

储存条件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.

Shipping ConditionEvaluation sample solution : ship with blue ice

All other available size: ship with RT , or blue ice upon request

产品描述:


5'-Thymidylic acid (dTMP) is a deoxyribonucleotide.1 It is formed via methylation of dUMP by thymidylate synthase. It is further phosphorylated by thymidine kinase (TK) to form dTDP during nucleic acid synthesis.2 Oral administration of dTMP in combination with dCMP increases lifespan in a Tk2 H126N knock-in mouse model of TK2 deficiency.31.Berg, J.M., Tymoczko, J.L., and Stryer, L.Nucleotide BiosynthesisBiochemistry(2002)

2.Lee, L.S., and Cheng, Y.Human thymidylate kinase. Purification, characterization, and kinetic behavior of the thymidylate kinase derived from chronic myelocytic leukemiaJ. Biol. Chem.252(16)5686-5691(1977)

3.Lopez-Gomez, C., Levy, R.J., Sanchez-Quintero, M.J., et al.Deoxycytidine and deoxythymidine treatment for thymidine kinase 2 deficiencyAnn. Neurol.81(5)641-652(2017)
特别提醒公司产品仅供科研使用


英文名称
5'-Thymidylic Acid (sodium salt)
货号
EY-01Y13089
CAS
33430-62-5
含量
>95.00%
规格
100mg、250mg、1g
品牌
上海一研
首页
购物车
加入购物车
立即购买