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产品属性：
产品名称 | 11-Dehydrocorticosterone |
规格 | 1mg、5mg、10mg |
货号 | EY-01Y13205 |
Cas No.: 72-23-1
别名: 11-DHC
化学名: 21-hydroxy-pregn-4-ene-3,11,20-trione
分子式: C21H28O4
分子量: 344.4
溶解度: Chloroform: slightly soluble,Methanol: slightly soluble
储存条件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
11-Dehydrocorticosterone is an endogenous mineralocorticoid.[1],[2],[3] It increases Na+/K+-ATPase mRNA expression in vascular smooth muscle cells and inhibits aldosterone action in B. marinus toad bladder tissue in a concentration-dependent manner.[1],[2] 11-Dehydrocorticosterone decreases the sodium/creatine ratio and increases the potassium/creatine ratio in rat urine in a dose-dependent manner in a model of 11β-hydroxysteroid dehydrogenase inhibition induced by carbenoxolone .[3] Chronic administration 11-dehydrocorticosterone increases plasma glucocorticoids levels, body weight gain, and adiposity, as well as induces insulin resistance in mice.[4]
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