- 产品详情
- 产品参数
- 产品评论
产品属性：
产品名称 | (Rac)-Finerenone |
规格 | 10mM*1 mL in DMSO、5 mg、10 mg、25 mg、50 mg、100 mg |
货号 | EY-01Y13539 |
Cas No.: 1050477-27-4
别名: N/A
化学名: N/A
分子式: C21H22N4O3
分子量: 378.42
溶解度: DMSO : 62.5 mg/mL (165.16 mM; Need ultrasonic)
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
(Rac)-Finerenone ((Rac)-BAY 94-8862) is the racemate of Finerenone. Finerenone is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist (IC50=18 nM). Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold)[1].[1]. BÄrfacker L, et al. Discovery of BAY 94-8862: a nonsteroidal antagonist of the mineralocorticoid receptor for the treatment of cardiorenal diseases. ChemMedChem. 2012;7(8):1385-1403.
特别提醒公司产品仅供科研使用
