产品属性:
产品名称 | 5,7-Dimethoxyflavone |
规格 | 10mM*1 mL in DMSO、25 mg、50 mg |
货号 | EY-01Y14239 |
Cas No.: 21392-57-4
别名: N/A
化学名: N/A
分子式: C17H14O4
分子量: 282.29
溶解度: DMSO: 100 mg/mL (354.25 mM)
储存条件: 4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
5,7-Dimethoxyflavone is one of the major components of Kaempferia parviflora, has anti-obesity, anti-inflammatory, and antineoplastic effects. 5,7-Dimethoxyflavone inhibits cytochrome P450 (CYP) 3As. 5,7-Dimethoxyflavone is also a potent Breast Cancer Resistance Protein (BCRP) inhibitor[1][2].[1]. Ochiai W, et al. Effect of the active ingredient of Kaempferia parviflora, 5,7-dimethoxyflavone, on the pharmacokinetics of midazolam. J Nat Med. 2018 Jun;72(3):607-614.
[2]. Bae S, et al. Effect of 5,7-dimethoxyflavone on Bcrp1-mediated transport of sorafenib in vitro and in vivo in mice. Eur J Pharm Sci. 2018 May 30;117:27-34.
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