上海一研生物科技有限公司

产品属性：

Cas No.: 1202864-50-3

别名: N/A

化学名: N/A

分子式: C14D7H15N2O3

分子量: 273.4

溶解度: Chloroform: slightly soluble,Methanol: slightly soluble

储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.

Shipping ConditionEvaluation sample solution : ship with blue ice

All other available size: ship with RT , or blue ice upon request

产品描述：

(±)-Atenolol-d7 is intended for use as an internal standard for the quantification of (±)-atenolol by GC- or LC-MS. (±)-Atenolol is an antagonist of the β1-adrenergic receptor (β1-AR; Ki = 1.14 µM).1 It is selective for β1-ARs over β2-ARs (Ki = 48.7 µM). (±)-Atenolol (200 mg/kg per day) delays the onset of hypertension in spontaneously hypertensive rats.2 Formulations containing atenolol have been used in the treatment of high blood pressure. 1.Golf, S., Bjornerheim, R., Erichsen, A., et al.Relative selectivity of different β-adrenoceptor antagonists for human heart β1- and β2-receptor subtypes assayed by a radioligand binding techniqueScand. J. Clin. Lab. Invest.47(7)719-723(1987)

2.Richer, C., Boissier, J.R., and Giudicelli, J.F.Chronic atenolol treatment and hypertension development in spontaneously hypertensive ratsEur. J. Pharmacol.47(4)393-400(1978)
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