产品属性:
产品名称 | ABC99 |
规格 | 500μg、1mg、5mg |
货号 | EY-01Y14179 |
Cas No.: 2331255-53-7
别名: N/A
化学名: 7-(4-chlorobenzyl)-1,3-dioxohexahydroimidazo[1,5-a]pyrazin-2(3H)-yl-2,3-dihydro-4H-benzo[b][1,4]oxazine-4-carboxylate
分子式: C22H21ClN4O5
分子量: 456.9
溶解度: 1mg/mL in Chloroform, 1mg/mL in acetonitrile, 1mg/mL in methyl acetate
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
ABC99 is an N-hydroxyhydantoin (NHH) carbamate that inhibits the Wnt-deacylating enzyme NOTUM (IC50 = 13 nM).[1] It preserves Wnt3A signaling in the presence of NOTUM (EC50 = 89 nM in a cell-based reporter assay).
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