产品属性:
产品名称 | (±)-Ibuprofen-d3 |
规格 | 1 mg、5 mg、10 mg、50 mg |
货号 | EY-01Y14274 |
Cas No.: 121662-14-4
别名: N/A
化学名: N/A
分子式: C13H15D3O2
分子量: 209.3
溶解度: DMF: >45 mg/ml,DMSO: >50 mg/ml,Ethanol: >60 mg/ml,PBS (pH 7.2): >2 mg/ml
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
Ibuprofen-d3 contains three deuterium atoms. It is intended for use as an internal standard for the quantification of ibuprofen by GC- or LC-mass spectrometry. Ibuprofen is a non-selective, reversible COX inhibitor. The IC50 values for human recombinant COX-1 and -2 are 2.6 and 1.53 µM, respectively.1 The Ki value for ovine COX-1 and -2 is 9 µM.21.Barnett, J., Chow, J., Ives, D., et al.Purification, characterization and selective inhibition of human prostaglandin G/H synthase 1 and 2 expressed in the baculovirus systemBiochim Biophys. Acta.1209(1)130-139(1994)
2.Johnson, J.L., Wimsatt, J., Buckel, S.D., et al.Purification and characterization of prostaglandin H synthase-2 from sheep placental cotyledonsArch. Biochem. Biophys.324(1)26-34(1995)
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