产品属性:
产品名称 | 17β-Estradiol-d2 |
规格 | 500 μg、1 mg、5 mg |
货号 | EY-01Y14446 |
Cas No.: 53866-33-4
别名: N/A
化学名: N/A
分子式: C18H22D2O2
分子量: 274.4
溶解度: DMF: 20 mg/ml,DMSO: 20 mg/ml,DMSO:PBS(pH 7.2) (1:4): 0.2 mg/ml,Ethanol: 2 mg/ml
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
17β-Estradiol-d2 is intended for use as an internal standard for the quantification of 17β-estradiol by GC- or LC-MS. 17β-Estradiol is the major estrogen secreted by the premenopausal ovary. It is synthesized from testosterone primarily in the ovarian granulosa cells and placenta, but small amounts can be produced in the adrenal gland.1,2 Plasma 17β-estradiol levels increase gradually between days 1-7 of the menstrual cycle followed by a sharp increase to a peak value of about 300 pg/ml on day 12, just prior to ovulation.3,41.Vance, D.E.Cholesterol and related derivativesBiochemistry2nd ed.725-748(1988)
2.Miller, W.L., and Tyrrell, J.B.The adrenal cortexEndocrinology and Metabolism3rd edition555-711(1995)
3.Erickson, G.F.The ovary: Basic principles and concepts. A. PhysiologyEndocrinology and Metabolism3rd ed.973-1015(1995)
4.Munro, C.J., Stabenfeldt, G.H., Cragun, J.R., et al.Relationship of serum estradiol and progesterone concentrations to the excretion profiles of their major urinary metabolites as measured by enzyme immunoassay and radioimmunoassayClin. Chem.37(6)838-844(1991)
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