- 产品详情
- 产品参数
- 产品评论
产品属性：
产品名称 | ADAMTS-5 Inhibitor |
规格 | 500μg、1mg、5mg |
货号 | EY-01Y14659 |
Cas No.: 929634-33-3
别名: N/A
化学名: N/A
分子式: C16H11ClF3N3OS3
分子量: 449.9
溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml,Ethanol: 20 mg/ml
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5) is an aggrecanase in that it cleaves aggrecan, a major proteoglycan in cartilage. While it has key roles in cartilage destruction associated with osteoarthritis, ADAMTS-5 is also involved in other pathways, including neurological processes. ADAMTS-5 Inhibitor is an inhibitor of ADAMTS-5 (aggrecanase-2; IC50 = 1.1 µM) with 40-fold selectivity over ADAMTS-4 (aggrecanase-1).
特别提醒公司产品仅供科研使用
