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产品属性：
产品名称 | 7-Ethoxy-4-(trifluoromethyl)coumarin |
规格 | 5 mg、10 mg、25 mg、50 mg |
货号 | EY-01Y14745 |
Cas No.: 115453-82-2
别名: N/A
化学名: N/A
分子式: C12H9F3O3
分子量: 258.2
溶解度: Chloroform: slightly soluble,Methanol: slightly soluble
储存条件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
7-Ethoxy-5-(trifluoromethyl)coumarin is a fluorogenic substrate for cytochrome P450s (CYPs).1 Upon O-deethylation by CYPs, 7-hydroxy-4-(trifluoromethyl)coumarin (HFC) is released and its fluorescence can be used to quantify CYP activity. HFC displays excitation/emission maxima of 410/510 nm, respectively. 1.Buters, J.T.M., Schiller, C.D., and Chou, R.C.A highly sensitive tool for the assay of cytochrome P450 enzyme activity in rat, dog and man. Direct fluorescence monitoring of the deethylation of 7-ethoxy-4-trifluoromethylcoumarinBiochem. Pharmacol.46(9)1577-1584(1993)
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