产品属性:
产品名称 | Acetyl β-Endorphin (human) (trifluoroacetate salt) |
规格 | 1mg |
货号 | EY-01Y14794 |
Cas No.: N/A
别名: N/A
化学名: N/A
分子式: C160H253N39O47S•XCF3COOH
分子量: 3507
溶解度: Water: 1 mg/ml
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
Acetyl β-endorphin is an acetylated derivative of β-endorphin that binds to opioid receptors in rat caudal dorsomedial medulla (Ki = 490 nM) and mouse brain membrane preparations (IC50 = 109 nM). It induces chemotaxis of human monocytes in vitro when used at a concentration of 0.1 nM. In vivo, it reduces antinociception in mice induced by β-endorphin , morphine, [D-Ala2, N-Me-Phe4, Gly5-ol]-enkephalin , and [D-Ala2, D-Leu5]-enkephalin (DADLE) in a tail-flick test (ED50s = 2.08, 33.11, 0.03, and 0.07 mol per animal, respectively).
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