产品属性:
产品名称 | AGX51 |
规格 | 1mg、5mg、10mg、25mg、50mg、100mg |
货号 | EY-01Y14774 |
Cas No.: 330834-54-3
别名: N/A
化学名: N/A
分子式: C27H29NO4
分子量: 431.52
溶解度: DMSO: 250 mg/mL (579.35 mM); Ethanol: 100 mg/mL (231.74 mM); H2O: < 0.1 mg/mL (insoluble)
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
AGX51 is a first-in-class pan-Id (inhibitors of DNA-binding/differentiation proteins) antagonist and degrader. AGX51 inhibits the Id1-E47 interaction, leading to ubiquitin-mediated degradation of Ids, cell growth arrest, and reduces viability. AGX51 inhibits pathologic ocular neovascularization[1].[1]. Wojnarowicz PM, et al. A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization. Cell Rep. 2019 Oct 1;29(1):62-75.e7.
特别提醒公司产品仅供科研使用