- 产品详情
- 产品参数
- 产品评论
产品属性：
产品名称 | 15-deoxy-δ12,14-Prostaglandin J2-d4 |
规格 | 25 μg、50 μg、100 μg |
货号 | EY-01Y14865 |
Cas No.: 1542166-82-4
别名: N/A
化学名: N/A
分子式: C20H24D4O3
分子量: 320.5
溶解度: DMF: >100 mg/ml (from PGD2),DMSO: >50 mg/ml (from PGD2),Ethanol: >75 mg/ml (from PGD2),PBS pH 7.2: >2.7 mg/ml (from 15-deoxy-d12,
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
15-deoxy-δ12,14-PGJ2-d4 contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 15-deoxy-δ12,14-PGJ2 by GC- or LC-mass spectrometry. 15-deoxy-δ12,14-Prostaglandin J2 (15-deoxy-δ12,14-PGJ2) is a metabolite of PGJ2. 15-deoxy-δ12,14-PGJ2 is formed from PGD2 by the elimination of two molecules of water. It binds selectively to PPARγ with an EC50 of 2 µM in a murine chimera system.1,2 15-deoxy-δ12,14-PGJ2 is more potent than PGD2, δ12-PGJ2, and PGJ2 in stimulating lipogenesis in C3H10T1/2 cells. The EC50 for induction of adipocyte differentiation in cultured fibroblasts is 7 µM.11.Forman, B.M., Tontonoz, P., Chen, J., et al.15-Deoxy-δ12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARγCell83(5)803-812(1995)
2.Kliewer, S.A., Lenhard, J.M., Willson, T.M., et al.A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiationCell83(5)813-819(1995)
特别提醒公司产品仅供科研使用
