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产品属性：
产品名称 | AF40431 |
规格 | 1mg、5mg、10mg、25mg、50mg、100mg、200mg、500mg |
货号 | EY-01Y15065 |
Cas No.: 181125-92-8
别名: N/A
化学名: N/A
分子式: C17H21NO5
分子量: 319.35
溶解度: DMSO: 25 mg/mL (78.28 mM; ultrasonic and adjust pH to 1 with TFA)
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
AF40431, the first reported small-molecule ligand of sortilin, has an IC50 of 4.4 µM and a Kd of 0.7 µM . AF40431 is bound in the neurotensin-binding site of sortilin[1].[1]. Andersen JL, et al. Identification of the first small-molecule ligand of the neuronal receptor sortilin and structure determination of the receptor-ligand complex. Acta Crystallogr D Biol Crystallogr. 2014 Feb;70(Pt 2):451-60.
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