产品属性:
产品名称 | (R)-NVS-ZP7-4 |
规格 | Free Sample (0.1-0.5 mg)、5mg、10mg、25mg、50mg、100mg、200mg、500mg |
货号 | EY-01Y15122 |
Cas No.: N/A
别名: N/A
化学名: N/A
分子式: C28H28FN5OS
分子量: 501.62
溶解度: Soluble in DMSO
储存条件: -20°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
(R)-NVS-ZP7-4 is the R-isomer of NVS-ZP7-4. NVS-ZP7-4 is a Zinc transporter SLC39A7 (ZIP7) inhibitor that is also the first reported chemical tool to probe the impact of modulating ER zinc levels and investigate ZIP7 as a novel druggable node in the Notch pathway.[1]. Nolin E, et al. Discovery of a ZIP7 inhibitor from a Notch pathway screen. Nat Chem Biol. 2019 Feb;15(2):179-188.
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