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产品属性：
产品名称 | 7α-hydroxy Dehydroepiandrosterone |
规格 | 1 mg、5 mg、10 mg |
货号 | EY-01Y15440 |
Cas No.: 53-00-9
别名: N/A
化学名: N/A
分子式: C19H28O3
分子量: 304.4
溶解度: Ethanol: soluble
储存条件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
7α-hydroxy Dehydroepiandrosterone (7α-hydroxy DHEA) is an active metabolite of the endogenous steroid hormone dehydroepiandrosterone .1 7α-hydroxy DHEA is formed from dehydroepiandrosterone via 7-hydroxylation by cytochrome P450s (CYPs).2 It increases antigen-induced production of anti-tetanus toxoid and anti-pertussis antigen IgGs in co-cultures of human tonsil-derived B and T cells when used at a concentration of 1 µM.3 7α-hydroxy DHEA (6.25 mg/kg) increases serum concentrations of anti-lysozyme IgG in mice.11.Morfin, R., and Courchay, G.Pregnenolone and dehydroepiandrosterone as precursors of native 7-hydroxylated metabolites which increase the immune response in miceJ. Steroid Biochem. Mol. Biol.50(1-2)91-100(1994)
2.Hampl, R., Morfin, R., and Starka, L.7-Hydroxylated derivatives of dehydroepiandrosterone: What are they good for•Endocr. Regul.31(4)211-218(1997)
3.Lafaye, P., Chmielewski, V., Nato, F., et al.The 7α-hydroxysteroids produced in human tonsils enhance the immune response to tetanus toxoid and Bordetella pertussis antigensBiochim. Biophys. Acta1472(1-2)222-231(1999)
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