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产品属性：
产品名称 | 11-dehydro Thromboxane B2-d4 |
规格 | 25 μg、50 μg、100 μg、500 μg |
货号 | EY-01Y16166 |
Cas No.: 1240398-15-5
别名: N/A
化学名: N/A
分子式: C20H28D4O6
分子量: 372.5
溶解度: DMF: >50 mg/ml (from TXB2),DMSO: >25 mg/ml (from TXB2),Ethanol: >100 mg/ml (from TXB2),PBS pH 7.2: >100 μg/ml (from TXB2)
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
11-dehydro Thromboxane B2-d4 (TXB2-d4) is intended for use as an internal standard for the quantification of 11-dehydro TXB2 by stable isotope dilution MS. TXB2 is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2.1 11-dehydro TXB2 is one of the main plasma metabolites of TXB2 and can be used as a marker for in vivo TXA2 synthesis.1,2,3,4 The mean plasma level in human males is 0.9-4.3 pg/ml and the half life is 45-60 minutes.2,3,41.Ciabattoni, G., Pugliese, F., Davi, G., et al.Fractional conversion of thromboxane B2 to urinary 11-dehydrothromboxane B2 in manBiochimica et Biophysica Acta99266-70(1989)
2.Fitzgerald, G.A., Lawson, J., Blair, I.A., et al.Analysis of urinary metabolites of thromboxane and prostacyclin by negative-ion chemical-ionization gas chromatography/mass spectrometryAdvances in Prostaglandin, Thromboxane, and Leukotriene Research1587-90(1985)
3.Takasaki, W., Nakagawa, A., Tanaka, Y., et al.Enzyme immunoassay of human plasma 11-dehydrothromboxane B2Thrombosis Research63331-341(1991)
4.Catella, F., Healy, D., Lawson, J.A., et al.11-dehydro Thromboxane B2: A quantitative index of thromboxane A2 formation in the human circulationProceedings of the National Academy of Sciences of the United States of America835861-5865(1986)
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