产品属性:
产品名称 | 2-deoxy-2-fluoro L-Fucose |
规格 | 500μg、1mg、5mg、10mg |
货号 | EY-01Y15966 |
Cas No.: 70763-62-1
别名: N/A
化学名: N/A
分子式: C6H11FO4
分子量: 166.1
溶解度: DMF: 20 mg/ml,DMSO: 30 mg/ml,Ethanol: 0.25 mg/ml,PBS (pH 7.2): 10 mg/ml
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
Fucose is a deoxyhexose that is present in many organisms. Fucose-containing glycans, generated by fucosyltransferase using GDP-fucose, have roles in cell signaling, cell-cell interactions, and blood properties. 2-deoxy-2-fluoro L-Fucose is a fluorinated fucose analog. It can be metabolized inside the cell to a substrate-based inhibitor of fucosyltransferases. Alternatively, it can be converted in vitro to GDP-2-deoxy-2-fluoro L-fucose, a competitive inhibitor of α1,3-fucosyltransferase V (Ki = 4.2 µM).
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