上海一研生物科技有限公司

产品属性：

Cas No.: 2089389-15-9

别名: N/A

化学名: N/A

分子式: C18H21N5

分子量: 307.4

溶解度: Soluble in DMSO

储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.

Shipping ConditionEvaluation sample solution : ship with blue ice

All other available size: ship with RT , or blue ice upon request

产品描述：

Mas-related G protein-coupled receptor X2 (MRGPRX2) agonist (EC50 = 0.74 μM). Displays selectivity for MRGPRX2 over 350 other GPCRs, including MRGPRX1. Induces intracellular calcium release and degranulation in LAD2 mast cells in vitro. Negative control (S)-ZINC 3573 also available.Lansu et al (2017) In silico design of novel probes for the atypical opioid receptor MRGPRX2. Nat.Chem.Biol. 13 529 PMID:28288109
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