产品属性:
产品名称 | ABD459 |
规格 | 1mg、5mg、10mg |
货号 | EY-01Y16415 |
Cas No.: 1047670-51-8
别名: N/A
化学名: N/A
分子式: C24H17BrCl2N2O2
分子量: 516.2
溶解度: DMF: 3 mg/ml,DMF:PBS(pH7.2) (1:2): 0.33 mg/ml
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
ABD459 is a neutral antagonist of the central cannabinoid 1 (CB1) receptor (Ki = 8.6 nM). It inhibits food consumption in nonfasted mice without affecting motor activity. ABD459 reduces active food seeking for 5-6 hours after treatment, with no rebound after washout. ABD459 also diminishes rapid eye movement (REM) sleep, with no alterations of wakefulness or non-REM sleep.
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